By Malo, Jean-Luc
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Additional resources for Asthma in the Workplace, Fourth Edition
This may also influence crosssectional studies, if in, general, diseased or symptomatic individuals remember their exposures better than those without diseases. This would lead to overestimation of the effect. Using objective sources to collect data on exposures will reduce this type of differential misclassification. Confounding This refers to a situation where extraneous variable/s associate/s (positively or negatively) with the exposure of interest and is/ are determinant of the outcome of interest (Fig.
It is important to have trained technicians to calibrate the equipment and deal with potential problems. The technicians should also be trained to recognize poor subject performance (60). Poor performance, in particular, poor reproducibility, may also be a marker of airway dysfunction (61). Several factors need to be considered in choosing the lung function tests: the cost of equipment, the testing time, the simplicity of the test, and analysis of results, reproducibility, acceptability, and the degree of standardization of the instrument and test procedures.
Long-term outcomes of acute irritant-induced asthma. Am J Respir Crit Care Med 2009; 179: 923–8. 88. Takeda N, Maghni K, Daigle S, et al. Long-term pathologic consequences of acute irritant-induced asthma. J Allergy Clin Immunol 2009; 124: 975–81. 89. Leroyer C, Perfetti L, Cartier A, Malo JL. Can reactive airways dysfunction syndrome (RADS) transform into occupational asthma due to “sensitisation” to isocyanates? Thorax 1998; 53: 152–3. 90. Pepys J. Clinical and therapeutic significance of patterns of allergic reactions of the lungs to extrinsic agents.