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Animal Cell Technology: Basic & Applied Aspects: Proceedings by Johanna Myllyharju (auth.), Kazumi Yagasaki, Yutaka Miura,

By Johanna Myllyharju (auth.), Kazumi Yagasaki, Yutaka Miura, Makoto Hatori, Yoshihiro Nomura (eds.)

Animal telephone expertise is a transforming into self-discipline of telephone biology which goals not just to appreciate buildings, services and behaviors of differentiated animal cells, but in addition to examine their skills for use in business and scientific reasons. The target of animal telephone know-how contains accomplishments of clonal growth of differentiated cells with precious skill, optimization in their tradition stipulations, modulation in their skill for construction of medically and pharmaceutically vital proteins and the applying of animal cells to gene treatment, man made organs and sensible meals.
This quantity offers the readers an entire assessment of current state of the art in Japan and different international locations the place this box is easily complex. The complaints may be worthy for the mobile biologists, biochemists, molecular biologists, immunologists, biochemical engineers and different disciplines relating to animal mobilephone tradition, operating in both educational environments or in industries of biotechnology and pharmacy.

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Additional resources for Animal Cell Technology: Basic & Applied Aspects: Proceedings of the Fifteenth Annual Meeting of the Japanese Association for Animal Cell Technology (JAACT), Fuchu, Japan, November 11–15, 2002

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2. Anticancer effects of lignans in experimental cancer models In the DMBA-induced mammary carcinoma in rats, Thompson et al. (1996a and 1996b) were the first to demonstrate a chemopreventive action of secoisolariciresinol diglycoside (SDG). o. 5 mg/rat) starting one week after DMBA induction significantly decreased the number of tumors per tumor-bearing rat and per number of rats in the group. There were no differences in the average tumor volumes between the SDG-treated and control groups. We have shown that 7-hydroxymatairesinol (HMR), which was extracted from heartwood of spruce tree (Picea abies) and converted to ENL in rat, inhibited the progression of chemically induced rat mammary carcinoma (Saarinen et al.

Introduction WW domains are universal protein modules for binding Pro-rich ligands. eu-Pro; Group III, Pro-rich sequences with Arg, and Group Iv, pSer/pThr-Pro (PS/pT-P). Arg14 and Arg17, on the WW domain of Pinl, are thought to be important for the binding of Group N ligands that have pSer/pThr-Pro sequences. We have applied surface plasmon resonance to determine the ligand specificity of several WW domains containing Arg14. Based on the results from the SPR binding assay and the homology modeling, we proposed the common ligand recognition mechanism for the Group N WW domains by comparing it to that of the Group I WW domains.

When peritoneal macrophages were pre-treated with caffeic acid, rosmarinic acid, or luteolin at 20-500 f1 glml for 1 hour, these components inhibited the LPS-stimulated TNF- a production in a dose dependent manner. Further HPLC analysis of the WM-W fraction revealed the existence of luteolin 7-0- Bglucuronide. Our investigation of the isolated glucoside, found that it has no activity. 3. INHIBITORY ACIVITY OF LUTEOUN ON TNF- a PRODUCTION AND EAR EDEMA When mice were primed with an oral administration of romurtide (500 f1 g /mouse) and then triggered with an intravenous injection of OK-432 (3 KE/mouse), TNF- a was induced in the serum.

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