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Adipokines by Victor R. Preedy, Ross J. Hunter

By Victor R. Preedy, Ross J. Hunter

Adipokines (also known as adipocytokines) are a gaggle of peptides secreted via adipose tissue. they've got varied roles, from features within the person phone to the total physique. This quantity examines quite a lot of particular adipokines in addition to their common mobile features, together with thermal pressure and adipokine expression, primary frightened procedure roles for adiponectin in neuroendocrine and autonomic functionality, and astroglial leptin receptors. It discusses comparable ailments and prerequisites corresponding to nonalcoholic fatty liver illness, metabolic syndrome, middle and rheumatic ailments, and bronchial asthma and sleep problems.

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Extra resources for Adipokines

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2012 by Taylor & Francis Group, LLC Apelin as an Adipokine 47 APELIN AND AT In 2005 apelin was identified as a new adipokine expressed and secreted by human and mouse mature adipocytes (Boucher et al. 2005). Apelin mRNA is detectable in non-differentiated preadipocytes, but its production increases 4-fold upon differentiation of adipocytes, as previously described for the well-characterized adipokines leptin and adiponectin. So far few data are available concerning apelin production and regulation in AT.

Turban, P. Saint-Marc, A. Fukamizu, R. Negrel, G. Ailhaud, and M. Teboul. 2001b. Angiotensinogen-deficient mice exhibit impairment of diet-induced weight gain with alteration in adipose tissue development and increased locomotor activity. Endocrinology 142: 5220-5225. Masuzaki, H. and H. J. K. M. M. Paterson, H. G. Sharp, S. J. Mullins, et al. 2003. Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice. J. Clin. Invest. 112: 83-90. Ogihara, T. and T.

Metab. Res. 41: 1-6. Li, Y. and K. Totsune, K. Takeda, and K. Furuyama. 2003. Differential expression of adrenomedullin and resistin in 3T3-L1 adipocytes treated with tumor necrosis factor-α. Eur. J. Endocr. 149: 231-238. C. G. Morgenthaler, T. S. Wu. 2007. The relationship between adrenomedullin, metabolic factors, and vascular function in individuals with type 2 diabetes. Diabetes Care 30: 1513-1519. Linscheid, P. and D. Seboek, H. Zulewski, and U. Keller. 2005. Autocrine/paracrine role of inflammation-mediated calcitonin gene-related pepetide and adrenomedullin expression in human adipose tissue.

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